Product Overview

As a leading Vitamin H supplier, Liyinbio offers high-quality D-Biotin (Vitamin H).D-Biotin (Vitamin B7, Vitamin H) is a water-soluble vitamin that plays a critical role as an essential coenzyme for five carboxylase enzymes in the human body. These enzymes are fundamental to three key metabolic processes:

Energy Metabolism: As a cofactor for pyruvate carboxylase, biotin is essential for gluconeogenesis — the synthesis of glucose from non-carbohydrate sources — and for the metabolism of carbohydrates, fats, and proteins for energy production.

Fatty Acid Synthesis: It serves as a coenzyme for acetyl-CoA carboxylase, which is involved in the biosynthesis of fatty acids, crucial for maintaining cell membrane integrity and function.

Amino Acid Catabolism: Biotin-dependent enzymes, such as propionyl-CoA carboxylase and 3-methylcrotonyl-CoA carboxylase, are involved in the breakdown of specific amino acids.

By supporting these fundamental cellular processes, D-Biotin is indispensable for normal growth, development, and overall metabolic health in both humans and animals.

At Henan Liyin Biotech, we supply high-purity D-Biotin in the form of a white crystalline powder, with a minimum purity of ≥98%, compliant with USP, EP, and FCC standards. Our product is manufactured under strict GMP guidelines, ensuring batch-to-batch consistency and stability for demanding supplement, feed, and food applications.

Key Product Features

Verified High Purity: Assay ≥98.0% (by HPLC), ensuring consistent potency and efficacy.

Multi-Standard Compliance: Meets USP, EP, and FCC specifications, providing global regulatory acceptance.

Excellent Stability: Maintains potency under recommended storage conditions, making it suitable for complex multi-nutrient blends and processed foods.

Complete Traceability: Every batch is accompanied by a comprehensive Certificate of Analysis (COA) and Material Safety Data Sheet (MSDS).

Flexible Packaging: Available in packaging options to suit your production needs — from laboratory samples to bulk industrial quantities.

Our Commitment to Quality: Data-Driven Reliability

At Henan Liyin Biotech, our commitment to quality is reflected in every batch we produce. Take our recent D-Biotin batch (No. 0526030027), for example. While the USP standard requires a minimum assay of 98.0%, our batch consistently achieved an outstanding 99.7% purity — delivering superior potency for your formulations.

Our rigorous quality control goes far beyond purity. We maintain total impurities at just 0.7% (well below the ≤1.0% USP limit), with individual impurities like related substances controlled to 0.3%. This ensures a cleaner, more reliable product for sensitive supplement, feed, and food applications.

We also strictly monitor physical properties critical to manufacturing: our Loss on Drying is just 0.04% (far below the ≤0.2% limit), ensuring excellent flowability and stability during blending and storage. Our heavy metal controls are equally stringent, with lead and arsenic both measured at <0.02 mg/kg — a fraction of the allowed limits.

Every batch we ship is backed by this same level of detailed testing and full traceability, giving you the confidence to formulate without variability.

Why Choose Us as Your Vitamin H Biotin Supplier?

• Stringent Quality Control: Our D-Biotin is produced under strict GMP guidelines, with purity guaranteed at ≥99% through HPLC testing. Each batch comes with a full Certificate of Analysis (COA).
• Competitive Pricing: As a direct manufacturer, we eliminate middleman costs, offering factory-direct prices without compromising on quality.
• Stable Supply Chain: With an annual production capacity of [X] tons, we ensure on-time delivery for both small R&D samples and large-scale commercial orders.
• Global Compliance: Our products meet USP, EP, and FCC standards, suitable for export to markets worldwide.

Dietary Supplements

D-Biotin is a cornerstone ingredient in supplements targeting hair, skin, and nail health, as well as in general wellness formulations. Its role as a coenzyme in energy metabolism and fatty acid synthesis makes it a valuable addition to B-complex vitamins and multivitamins. It is frequently combined with other nutrients that support its function:

Synergistic Formulations: Often paired with zinc (for hair and skin health), collagen (for structural support), and silicon (for connective tissue), creating comprehensive beauty-from-within products.

Target Formats: Widely used in tablets, capsules, gummies, and liquid drops, with typical dosages ranging from 30 to 100 μg per serving for general wellness, and up to 300 μg per serving in specialized high-potency supplements.

Formulation Advantage: Our D-Biotin exhibits excellent stability and compatibility with other vitamins and minerals, making it a reliable choice for complex multi-nutrient blends.

Animal Feed

In animal nutrition, D-Biotin is an essential additive that plays a critical role in preventing deficiency syndromes and supporting productivity. Its benefits are particularly well-documented in poultry and swine production:

Poultry: Prevents biotin deficiency, which can cause poor growth, dermatitis, and footpad lesions, reducing animal welfare and productivity. It is also vital for maintaining egg hatchability and shell quality in breeding stock. Typical supplementation levels in poultry feeds range from 50–200 μg/kg of complete feed.

Swine: Supports hoof integrity and overall growth performance. Biotin is often included in sow diets to improve litter quality and reduce foot lesions.

Aquaculture: Used in fish and shrimp feeds to support metabolic health and stress resistance.

Recommended Inclusion: Inclusion rates vary by species, production stage, and diet composition. Our Feed Grade D-Biotin is formulated for optimal dispersion in premixes and pelleted feeds.

Food Fortification

D-Biotin is a mandatory fortificant in many countries, added to staple foods to support population-level health and prevent deficiency. Its high stability makes it suitable for processed foods:

Key Applications: Widely used to fortify infant formula, breakfast cereals, cereal bars, and other functional foods to meet regulatory nutrition standards.

Typical Fortification Levels: In infant formula, levels are strictly regulated and typically range from 5–20 μg per 100 kcal (depending on national regulations). In breakfast cereals, levels often range from 10–50 μg per 100 grams.

Formulation Stability: Our D-Biotin demonstrates excellent stability in dry, heat-processed foods and is compatible with other B-vitamins commonly used in fortification blends.