Product Overview

D-Panthenol (Provitamin B5) is a highly effective humectant and skin-conditioning agent widely used in cosmetic and personal care formulations. It is a stable, viscous liquid that is readily soluble in water and alcohol. Upon application to the skin or hair, D-Panthenol is rapidly absorbed and enzymatically converted into Pantothenic Acid (Vitamin B5) , a vital component of Coenzyme A.

As a key player in cellular metabolism, Coenzyme A is essential for the synthesis of lipids, proteins, and other critical biomolecules. This mechanism underpins D-Panthenol's ability to support the regeneration of the epidermal barrier, promote wound healing, and maintain healthy skin and hair tissues.

At Henan Liyin Biotech, we supply high-purity D-Panthenol in the form of a clear, viscous liquid, with a minimum purity of ≥98%, compliant with USP and EP standards. Our product is manufactured under strict GMP guidelines, ensuring batch-to-batch consistency and stability for demanding cosmetic formulations.

Key Functional Properties

Moisturization: Acts as a hygroscopic humectant, attracting and retaining moisture in the stratum corneum. This improves skin hydration and reduces transepidermal water loss (TEWL), leaving the skin feeling soft and smooth.

Soothing & Repair: Demonstrates anti-inflammatory properties that soothe irritated skin and promote the regeneration of the epidermal barrier. This makes it particularly suitable for sensitive, damaged, or sun-exposed skin.

Hair Conditioning: Penetrates the hair shaft to increase its moisture-holding capacity, improving hair's elasticity, shine, and manageability while reducing split ends and surface damage.

Why Choose Our D-Panthenol?

Verified Purity: Assay ≥98.0% (by HPLC), ensuring consistent potency for all formulation types.

Excellent Solubility: Readily soluble in water and alcohol, facilitating easy incorporation into a wide range of skincare, haircare, and personal care products.

Proven Efficacy: Backed by decades of use and research, D-Panthenol is a trusted, well-documented ingredient with a strong safety profile.

Complete Traceability: Every batch is accompanied by a comprehensive Certificate of Analysis (COA) and Material Safety Data Sheet (MSDS).

Flexible Supply: Available in packaging options to suit your production needs, from laboratory samples to bulk industrial quantities.

D-Panthenol (Provitamin B5) is a highly effective humectant and skin-conditioning agent. Upon application, it is rapidly absorbed and converted into Pantothenic Acid (Vitamin B5) in the skin and hair tissues. As a vital component of Coenzyme A, it plays a key role in cellular metabolism, promoting the synthesis of lipids and proteins essential for maintaining a healthy skin barrier and repairing damaged tissue.

Key functional properties:

Moisturization: Acts as a hygroscopic humectant, attracting and retaining moisture in the stratum corneum, which improves skin hydration and reduces transepidermal water loss (TEWL).

Soothing & Repair: Demonstrates anti-inflammatory properties that soothe irritated skin and promote the regeneration of the epidermal barrier, making it ideal for sensitive or compromised skin.

Hair Conditioning: Penetrates the hair shaft to increase its moisture-holding capacity, improving hair's elasticity, shine, and manageability while reducing split ends and surface damage.

Skin Care

D-Panthenol is a highly valued ingredient in skin care formulations due to its exceptional moisturizing, soothing, and barrier-repairing properties. Its ability to penetrate the stratum corneum and convert to Pantothenic Acid (Vitamin B5) makes it a key component of Coenzyme A, supporting lipid and protein synthesis essential for healthy skin.

Key Benefits: Provides deep hydration by acting as a humectant, reducing transepidermal water loss (TEWL). Demonstrates anti-inflammatory properties that soothe irritated skin, making it ideal for sensitive, damaged, or sun-exposed skin. Supports the regeneration of the epidermal barrier, promoting faster recovery.

Typical Concentration: Recommended usage levels range from 0.5% to 5% in the water phase of formulations.

Target Products: Widely used in moisturizers, anti-aging creams, serums, sunscreens, after-sun lotions, and baby care products. It is compatible with most cosmetic ingredients and can be incorporated into both leave-on and rinse-off products.

️ Hair Care

In hair care, D-Panthenol is recognized for its ability to penetrate the hair shaft and improve moisture retention, resulting in healthier, more manageable hair. Its film-forming properties also provide a protective layer that enhances shine and reduces surface damage.

Key Benefits: Increases the hair's moisture-holding capacity, improving elasticity, shine, and manageability. Helps reduce split ends and surface damage. Soothes the scalp and supports a healthy scalp environment.

Typical Concentration: Recommended usage levels range from 0.1% to 1% in the water phase.

Target Products: Commonly used in shampoos, conditioners, hair masks, leave-in treatments, and styling products. It is suitable for both clear and opaque formulations and works well in combination with other conditioning agents.

Personal Care & Other Applications

Beyond skin and hair care, D-Panthenol's mildness and protective properties make it a versatile addition to a wide range of personal care and specialty products. Its excellent skin compatibility and moisturizing effects are valued in multiple formats.

Key Benefits: Provides gentle moisturization and soothing effects, making it suitable for sensitive skin applications. Acts as a humectant and conditioner, improving product feel and skin comfort.

Typical Concentration: Usage levels vary by product type, typically ranging from 0.1% to 2% .

Target Products: Included in body lotions, lip balms, hand creams, shaving products, and baby care formulations.

Pharmaceuticals & Supplements: Occasionally used in topical ointments and as a nutritional supplement, leveraging its role as a precursor to Vitamin B5.