Coenzyme Q10 Bulk Powder: What B2B Buyers Need to Know About Purity, CAS 303-98-0
Jun 14,2026
Coenzyme Q10 (CoQ10, CAS 303-98-0) is one of the most sought-after ingredients in the global nutraceutical and functional food market. As a fat-soluble, vitamin-like compound found in every cell of the human body, it plays an indispensable role in mitochondrial energy production and antioxidant defense.
For B2B buyers — supplement brands, contract manufacturers, and raw material distributors — understanding the technical specifications, grades, and sourcing nuances of Co Q10 is critical to making informed procurement decisions. This guide provides a comprehensive overview.
What Is Coenzyme Q10?
Coenzyme Q10, also known as Ubiquinone, is a naturally occurring compound concentrated in the mitochondria — the "power plants" of cells. Its primary biological functions include:
- **ATP Energy Production:** CoQ10 accepts electrons during oxidative phosphorylation, enabling cellular energy synthesis
- **Antioxidant Protection:** It neutralizes free radicals and protects cell membranes from lipid peroxidation
- **Cardiovascular Support:** CoQ10 is essential for heart muscle function, which requires high energy output
Commercial CoQ10 is produced via microbial fermentation, yielding a bright yellow-orange crystalline powder.

CoQ10 Specifications: What to Look For
Purity Grades
| Specification | Purity (HPLC) | Typical Use |
| 98% Powder | ≥ 98% | Standard grade for supplements and capsules |
| 99% Powder | ≥ 99% | Premium grade for pharmaceutical applications |
| 10% Powder | ≥ 10% | Water-soluble form for beverages and premixes |
| USP Grade | Meets USP standards | Pharmaceutical and regulated markets |
Form: Ubiquinone vs. Ubiquinol
| Property | Ubiquinone (Oxidized) | Ubiquinol (Reduced) |
| Form | Standard CoQ10 | Active antioxidant form |
| Stability | Highly stable | Sensitive to light and air |
| Bio availability | Good; requires conversion | Ready for absorption |
| Best for | Healthy adults under 40 | Adults over 40 and those with health concerns |
| Cost | Lower | Higher |
Most bulk CoQ10 is supplied as Ubiquinone, which the body naturally converts to Ubiquinol.
Applications of CoQ10

Dietary Supplements
CoQ10 is a flagship ingredient in:
- Cardiovascular health formulas
- Anti-aging and longevity supplements
- Energy support and sports nutrition products
- Statin-induced CoQ10 depletion formulas
Typical dosages range from 30-200 mg per serving. Due to its fat-soluble nature, CoQ10 is most effectively delivered in oil-based softgels or combined with bio availability enhancers such as piperine (black pepper extract).
Cosmetics
In topical formulations, CoQ10 serves as an antioxidant that helps reduce fine lines and protect against environmental damage.
### Functional Foods and Beverages
Water-soluble CoQ10 (typically 10% concentration) is used in stick packs, instant drinks, and functional waters.
Bulk Sourcing Checklist

When evaluating CoQ10 suppliers, consider the following:
1. Manufacturing Method: Fermentation-sourced CoQ10 is preferred over synthetic for purity and natural label claims
2. Third-Party Testing: Request COA with heavy metal, microbial, and residual solvent analysis
3. Particle Size:Standard 80-100 mesh ensures uniformity in blending
4. Packaging:CoQ10 is light- and heat-sensitive — aluminum foil bags or opaque drums are essential
5. Supply Stability:CoQ10 demand fluctuates; choose a supplier with consistent production capa
Liyin Bio CoQ10 at a Glance
| Parameter | Specification |
| Product Name | Coenzyme Q10 (Ubiquinone) |
| CAS No. | 303-98-0 |
| Assay (HPLC) | ≥ 98% |
| Appearance | Yellow-orange crystalline powder |
| Particle Size | 80-100 mesh |
| Packing | 1 kg/foil bag, 25 kg/drum |
| MOQ | 1 kg (sample), 25 kg (bulk) |
| Sample | Free sample available |
Contact Us
For CoQ10 pricing, technical data sheets, or to request a sample:
Email:yolanda@liyinbio.com
Phone/WhatsApp:+86-15824830539
Website: www.liyinbio.com
Henan Liyin Biotech Co., Ltd — Premium ingredients, global delivery.
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