Vitamin B12, also known as Cobalamin, is one of the most chemically complex vitamins and the only B vitamin that contains a metal ion (cobalt). It is essential for red blood cell formation, neurological function, and DNA synthesis.

Unlike other vitamins, B12 cannot be produced by plants or animals — it is synthesized exclusively by microorganisms through fermentation. This makes sourcing high-quality B12 from a reliable manufacturer critical for B2B buyers in the food, feed, and pharmaceutical industries.

 What Is Cyanocobalamin?

Cyanocobalamin (CAS 68-19-9, Molecular Formula C63H88CoN14O14P) is the most common and stable form of Vitamin B12 used in commercial applications. It is produced through bacterial fermentation and purified to meet international standards.

The main forms of Vitamin B12 available in the market include:

| Form | Stability | Common Use |
|------|-----------|-------------|
| Cyanocobalamin | Most stable | Standard for supplements and fortification |
| Methylcobalamin | Less stable | Premium supplement form |
| Hydroxocobalamin | Moderate | Injectable formulations |

For bulk industrial applications, Cyanocobalamin is the preferred form due to its superior stability and cost-effectiveness.

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Vitamin B12 Specifications

Vitamin B12 is typically supplied at different concentration levels depending on the application:

| Specification | B12 Content | Typical Use |
|--------------|-------------|-------------|
| 0.1% Powder | 1,000 ppm | Feed premixes, food fortification |
| 1% Powder | 10,000 ppm | Dietary supplements, multivitamin blends |
| 99%+ Pure (USP) | ≥ 990,000 ppm | Pharmaceutical grade |

The 0.1% and 1% dilutions use food-grade carriers such as maltodextrin or dicalcium phosphate to ensure uniform distribution in final products.

Applications

 Feed Industry

In animal nutrition, Vitamin B12 is essential for:

- Promoting growth rate in poultry, swine, and cattle
- Preventing pernicious anemia
- Supporting reproductive performance
- Enhancing feed conversion ratio (FCR)

Recommended inclusion in feed ranges from 0.01-0.05 mg per kg of complete feed, depending on species.

 Food Fortification

B12 is added to:

- Fortified breakfast cereals
- Plant-based milk alternatives
- Energy bars and drinks
- Infant formulas
- Nutritional yeast products

The global trend toward plant-based diets has significantly increased demand for B12 fortification in vegan and vegetarian products.

 Pharmaceutical and Supplements

B12 is used in:

- Multivitamin tablets and capsules
- Sublingual B12 supplements
- Injectable B12 formulations
- B-complex injections

Bulk Sourcing Guide

 Quality Verification

When sourcing Vitamin B12, ensure the supplier provides:

- Certificate of Analysis (COA) with assay results
- Heavy metal analysis (lead, arsenic, mercury, cadmium)
- Microbial testing (total plate count, E. coli, Salmonella)
- Stability data
- Origin and production date

 Packaging

| Form | Typical Packaging |
|------|-------------------|
| 0.1% / 1% powder | 25 kg fiber drum with inner PE bag |
| 99% pure powder | 1 kg / 5 kg aluminum foil bag |
| Custom packaging | Available upon request |

### Storage Conditions

- Store in a cool, dry place below 25°C
- Keep container tightly sealed
- Protect from light and moisture
- Shelf life: typically 24-36 months from production date

Why Liyin Bio for Vitamin B12?

- Direct from manufacturer with competitive pricing
- Multiple dilution options (0.1%, 1%, pure)
- Full documentation package (COA, MSDS, spec sheet)
- Stable supply chain with short lead times
- Free samples available for qualification

 Contact Us

For Vitamin B12 pricing, samples, or technical consultation:

Email: yolanda@liyinbio.com  
Phone/WhatsApp: +86-15824830539  
Website: www.liyinbio.com

Henan Liyin Biotech Co., Ltd — From our factory to your formulation.
 

E-mail:
yolanda@liyinbio.com

TEL: 
+86-15824830539

Address:
Zhengzhou, China