High Purity L-Leucine Powder | ≥98.5% Feed, Food & Supplement Grade | CAS 61-90-5
Description:
Product Overview

L-Leucine is an essential branched-chain amino acid (BCAA) that cannot be synthesized by the body and must be obtained through diet or supplementation. It is one of the nine essential amino acids required for human health and plays a fundamental role in protein biosynthesis, metabolic regulation, and cellular signaling pathways. L-Leucine is particularly important for activating the mTOR signaling pathway — a key regulator of cell growth, proliferation, and metabolism.
In addition to its role in protein synthesis, L-leucine contributes to the regulation of blood-sugar levels, growth and repair of muscle and bone tissue, growth hormone production, and wound healing. It also helps prevent the breakdown of muscle proteins after trauma or severe stress.
At Henan Liyin Biotech, we supply high-purity L-Leucine in the form of a white crystalline powder, with a minimum purity of ≥98.5% (typically 98.5–101.5%), compliant with USP, EP, and FCC standards. Our product is available in Feed Grade, Food Grade, and Supplement Grade to serve applications across animal nutrition, human food, dietary supplements, and personal care.
Why Choose Our L-Leucine?
Verified Purity: Assay ≥98.5% (typically 99.0–100.5% by HPLC), ensuring consistent potency for all applications
Multi-Standard Compliance: Meets USP, EP, and FCC specifications, providing global regulatory acceptance
Proven Safety Profile: GRAS (Generally Recognized as Safe) for use in food applications
Complete Traceability: Each batch is accompanied by a comprehensive Certificate of Analysis (COA)
Flexible Packaging: Available in packaging options from 1kg to bulk quantities
Key Functional Properties

mTOR Signaling & Protein Synthesis
L-Leucine is unique among amino acids in its ability to directly activate the mTORC1 signaling pathway, a master regulator of cell growth, proliferation, and metabolism. This makes it particularly valuable for muscle protein synthesis and recovery. Leucine promotes ribosomal protein synthesis through activation of mTOR, stimulating protein synthesis in skeletal muscle.
Muscle Growth & Recovery
As a key BCAA, L-leucine supports muscle protein synthesis and recovery after exercise. It helps prevent the breakdown of muscle proteins after trauma or severe stress and contributes to the growth and repair of muscle and bone tissue.
Blood Sugar Regulation
L-leucine contributes to the regulation of blood-sugar levels through its metabolic actions. It has been used in the diagnosis and treatment of idiopathic hyperglycemia in children.
Growth & Development
L-leucine supports growth hormone production and is essential for normal growth and development in infants and children.

Wound Healing & Tissue Repair
Leucine plays a role in wound healing and tissue repair, supporting the body's recovery processes.
Quality Assurance & Documentation

All batches undergo rigorous quality control, including:
- Assay by HPLC: ≥98.5% (typical 99.0–100.5%)
- Heavy Metal Screening: Lead ≤ 10 ppm
- Optical Rotation: Verified against USP/EP/FCC specifications
- Loss on Drying and Residue on Ignition: To ensure stability and purity
We provide complete documentation with every shipment, including Certificate of Analysis (COA), Material Safety Data Sheet (MSDS), and Allergen Statement. Our GMP-certified production ensures batch-to-batch consistency and traceability.
Sourcing Support
We offer flexible packaging and can provide samples for pre-shipment testing. Our technical team is available to assist with grade selection (Feed, Food, or Supplement Grade), application guidance, and custom formulation support — from R&D trials to full-scale commercial production.
Contact us to discuss your specific L-Leucine requirements or to request samples for your formulations.
Parameters:
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Parameter
Specification
Product Name
L-Leucine
CAS Number
61-90-5
Molecular Formula
C₆H₁₃NO₂
Molecular Weight
131.17 g/mol
Assay (Purity)
≥ 98.5% (typically 99.0–100.5%)
Appearance
White crystals or crystalline powder
Available Grades
Feed Grade, Food Grade, Supplement Grade
Standards
USP, EP, FCC
Specific Rotation
[α]²⁰/D +14.9° to +16.0°
pH (1g/100mL)
5.5 – 6.5
Loss on Drying
≤ 0.2%
Residue on Ignition
≤ 0.1%
Heavy Metals
≤ 10 ppm
Lead (Pb)
≤ 5 mg/kg
Chlorides
≤ 0.020%
Sulfates
≤ 0.020%
Iron (Fe)
≤ 10 ppm
Melting Point
286-288°C (dec.)
Water Solubility
22.4 g/L at 20°C
Packaging Options
1kg, 5kg, 25kg (or as per request)
Documentation
Full COA, MSDS, Allergen Statement
Storage Conditions
Storage Conditions Store in a cool, dry place, protected from light and moisture. Avoid mixing with toxic or hazardous materials
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L-Leucine is an essential branched-chain amino acid (BCAA) that plays a unique role in activating the mTOR signaling pathway, a key regulator of cell growth and protein synthesis. It is critical for muscle protein synthesis, exercise recovery, and growth hormone production, while also supporting blood sugar regulation and wound healing. Available in Feed, Food, and Supplement Grades with ≥98.5% purity, backed by full documentation and batch-to-batch consistency.
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Dietary Supplements

L-Leucine is a popular ingredient in supplements targeting muscle growth, sports performance, and recovery. Its role as a BCAA and mTOR activator makes it valuable in:
- Sports Nutrition: Supports muscle protein synthesis, exercise performance, and post-workout recovery
- BCAA Formulations: Often combined with L-Isoleucine and L-Valine for comprehensive branched-chain amino acid support
- Muscle Preservation: Helps prevent muscle breakdown during periods of stress or calorie restriction
- Recovery Support: Supports tissue repair and wound healing
Typical Dosage: Adult requirement is approximately 2.2g/day. Supplementation levels vary by intended use; generally recognized as safe when taken as directed.
Food & Beverage

L-Leucine is widely used in the food industry as a nutritional supplement and flavoring agent (FEMA).
Key Applications:
- Amino Acid Infusions: Used in amino acid infusion solutions and comprehensive amino acid preparations
- Food Fortification: Added to processed foods and protein-based products to enhance nutritional profiles
- Flavoring Agent: Contributes to taste development in processed products
- Clinical Nutrition: Used in specialized nutrition formulas for patients with metabolic disorders
Regulatory Status: FCC grade is suitable for food, beverage, and nutritional supplement applications. Permitted for use as a nutrient supplement under FDA regulations.
Animal Feed

L-Leucine is authorized as a nutritional feed additive for all animal species. It is one of the essential amino acids required for optimal growth and production.
Key Applications:
- Nutritional Supplement: Provides an essential amino acid source in animal diets
- Growth Performance: Supports growth and development in poultry, swine, and other livestock
- Broad Species Use: Suitable for all animal species, including poultry, swine, and aquaculture
Recommended Inclusion: Levels vary by species and production stage. Our Feed Grade L-Leucine is formulated for optimal dispersion in premixes and pelleted feeds.
Personal Care & Cosmetics
L-Leucine is used in personal care formulations for its skin-conditioning, hair-conditioning, and fragrance properties.
Key Applications:
- Hair Conditioning: Functions as a hair conditioning agent
- Skin Conditioning: Used in skin care products for its skin-conditioning properties
- Fragrance: May contribute to product fragrance profiles
- Nutritional Support: Used in topical formulations supporting skin health
Formula Compatibility: Stable in topical formulations and compatible with a wide range of cosmetic ingredients.
- Sports Nutrition: Supports muscle protein synthesis, exercise performance, and post-workout recovery
Key words:
High Purity L-Leucine Powder | ≥98.5% Feed, Food & Supplement Grade | CAS 61-90-5
Function:
L-Leucine is an essential branched-chain amino acid (BCAA) that plays a unique role in activating the mTOR signaling pathway, a key regulator of cell growth and protein synthesis. It is critical for muscle protein synthesis, exercise recovery, and growth hormone production, while also supporting blood sugar regulation and wound healing. Available in Feed, Food, and Supplement Grades with ≥98.5% purity, backed by full documentation and batch-to-batch consistency.
Application:
Dietary Supplements

L-Leucine is a popular ingredient in supplements targeting muscle growth, sports performance, and recovery. Its role as a BCAA and mTOR activator makes it valuable in:
- Sports Nutrition: Supports muscle protein synthesis, exercise performance, and post-workout recovery
- BCAA Formulations: Often combined with L-Isoleucine and L-Valine for comprehensive branched-chain amino acid support
- Muscle Preservation: Helps prevent muscle breakdown during periods of stress or calorie restriction
- Recovery Support: Supports tissue repair and wound healing
Typical Dosage: Adult requirement is approximately 2.2g/day. Supplementation levels vary by intended use; generally recognized as safe when taken as directed.
Food & Beverage

L-Leucine is widely used in the food industry as a nutritional supplement and flavoring agent (FEMA).
Key Applications:
- Amino Acid Infusions: Used in amino acid infusion solutions and comprehensive amino acid preparations
- Food Fortification: Added to processed foods and protein-based products to enhance nutritional profiles
- Flavoring Agent: Contributes to taste development in processed products
- Clinical Nutrition: Used in specialized nutrition formulas for patients with metabolic disorders
Regulatory Status: FCC grade is suitable for food, beverage, and nutritional supplement applications. Permitted for use as a nutrient supplement under FDA regulations.
Animal Feed

L-Leucine is authorized as a nutritional feed additive for all animal species. It is one of the essential amino acids required for optimal growth and production.
Key Applications:
- Nutritional Supplement: Provides an essential amino acid source in animal diets
- Growth Performance: Supports growth and development in poultry, swine, and other livestock
- Broad Species Use: Suitable for all animal species, including poultry, swine, and aquaculture
Recommended Inclusion: Levels vary by species and production stage. Our Feed Grade L-Leucine is formulated for optimal dispersion in premixes and pelleted feeds.
Personal Care & Cosmetics
L-Leucine is used in personal care formulations for its skin-conditioning, hair-conditioning, and fragrance properties.
Key Applications:
- Hair Conditioning: Functions as a hair conditioning agent
- Skin Conditioning: Used in skin care products for its skin-conditioning properties
- Fragrance: May contribute to product fragrance profiles
- Nutritional Support: Used in topical formulations supporting skin health
Formula Compatibility: Stable in topical formulations and compatible with a wide range of cosmetic ingredients.
About Us
Henan Liyin Biotech Co.,Ltd
We are is established in 2024,located in Zhengzhou,on the banks of the Yellow River-the revered “Mother River “of China .As a specialized supplier of human nutrition and animal health products ,the company focuses on a range of products including vitamins ,amino acids ,plant extracts ,and sweeteners,which are widely used in industries ,such as food ,health supplements,cosmetics ,feed and veterinary medicine .By integrating global product resources with the needs of international clients ,Liyin Biotech provides premium products and professional services tailored to each customer .
FAQ
How to contact ?
You can contact with us by Whatsapp:+86 15824830539, the Average Response Time is 0-4h on Work time, <24h on Non-worktime.
For every inquiry, our sales will provide the one-for-one service for you.
How about the payment terms ?
Normal orders: Company account ;Sample/small orders: Paypal(The 5-10% extrafee).About the payment term, we will negotiate alone.
How to get the samples ?
At the first time ,we can provide you the normal product <30g free sample
How to confirm the Product Quality before placing orders?
1st, you can get free samples for some products, just paythe basic cost for us.
2nd,Also you can send the specification or your quest tous, we will customize the products for you.3rd,We emphasis that our whole company make a livingwith organic chemical and customers, we absolutelyimpossible to sale any fake goods, unqualified goods, it isshame! And None False certificate/lie/illegal thing in oursales net!
Which kind of payment do you accept?
- As usually we use company account ,T/T in advance ,or at least 30% T/T in advance ,the balance can be paid by the copy of B/L
- For some countrys we can accept L/C at sight & DP at sight
- For smaples we can use Paypal (The 5-10% extra fees) or other ways
About the payment term, we will negotiate alone.
How about the shipment ?
1>For bulk goods ,we can use contaioner by sea ,1&20 and 1&40 contaioner
2>For urgently and expensive goods ,we can arrange the air lines for customers choose ,or can as customer required
3>For samples or small quantity goods ,we can use Fedex or other express ways
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