High Purity L-Lysine HCl Powder | ≥98.5% Feed, Food & Supplement Grade | CAS 657-27-2
Description:
Product Overview

L-Lysine Hydrochloride is the stable, readily soluble salt form of the essential amino acid L-Lysine. As an essential amino acid, it cannot be synthesized by the body and must be obtained through diet or supplementation . L-Lysine HCl plays a fundamental role in protein synthesis, collagen formation, calcium absorption, and immune function, making it indispensable for growth, recovery, and overall health in both humans and animals .
In animal nutrition, L-Lysine is recognized as the first limiting amino acid for pigs and the second limiting amino acid for poultry — meaning it is the most critical amino acid that must be supplemented in feed formulations to optimize growth performance and feed efficiency . Supplementing L-Lysine allows feed manufacturers to use lower-cost feed ingredients while maintaining desired growth rates and protein levels within livestock .
At Henan Liyin Biotech, we supply high-purity L-Lysine HCl in the form of a white crystalline powder, with a minimum purity of ≥98.5% (typically 98.5–101.5%), compliant with USP, EP, and FCC standards . Our product is available in Feed Grade, Food Grade, and Supplement Grade to serve applications across animal nutrition, human food, dietary supplements, and personal care.
Why Choose Our L-Lysine HCl?
Verified Purity: Assay ≥98.5% (typically 98.5–101.5% by HPLC), ensuring consistent potency for all applications
Excellent Solubility: Freely soluble in water (up to 100 mg/mL), facilitating easy incorporation into feed premixes, beverages, and supplement formulations
Multi-Standard Compliance: Meets USP, EP, and FCC specifications, providing global regulatory acceptance
Proven Safety Profile: L-Lysine HCl is well-tolerated at recommended dosages and safe for target species and consumers when used as a nutritional feed additive
Complete Traceability: Each batch is accompanied by a comprehensive Certificate of Analysis (COA)
Flexible Packaging: Available in packaging options from 1kg to bulk quantities
Key Functional Properties

Protein Synthesis & Muscle Growth
L-Lysine is one of the most important amino acids for protein synthesis. It is incorporated into the structural proteins of muscles and supports growth as well as regeneration after physical exertion. As a primary component of muscle tissue, it is essential for maintenance and development of lean muscle mass .
Collagen Formation & Skin Health
L-Lysine is a critical component of collagen production — the structural protein that keeps skin, bones, tendons, and connective tissue firm and elastic. It activates enzymes that stabilize collagen structures, supporting wound healing, skin regeneration, and tissue repair .
Calcium Absorption & Bone Health
L-Lysine promotes the absorption of calcium in the intestines and its incorporation into bones. This supports bone density and helps maintain skeletal health, particularly important in combination with vitamin D and K2 for optimal bone metabolism .
Immune Support & Viral Defense
L-Lysine plays a role in the production of antibodies, strengthening the immune system. It inhibits the replication of the herpes simplex virus (HSV-1) by competing with the amino acid L-Arginine for cellular uptake — arginine is required by the virus for its replication. Therefore, L-Lysine is frequently used to help prevent herpes outbreaks or shorten their duration .
Carnitine Precursor & Energy Metabolism
L-Lysine is a precursor of L-Carnitine, an amino acid derivative needed for the normal metabolism of fatty acids for energy production in the body .

Stress Reduction & Mood Support
- Lysine has a calming effect on the central nervous system by modulating the stress response via cortisol levels. Studies show that, in combination with L-Arginine, it can help reduce anxiety and stress symptoms .
Quality Assurance & Documentation

All batches undergo rigorous quality control, including:
Assay by HPLC: ≥98.5% (typically 98.5–101.5%)
Heavy Metal Screening: Lead ≤ 5 mg/kg
Microbiological Testing: Total plate count ≤ 500 CFU/g; Salmonella negative
Specific Rotation and pH: Verified against USP/EP/FCC specifications
Loss on Drying and Residue on Ignition: To ensure stability and purity
We provide complete documentation with every shipment, including Certificate of Analysis (COA), Material Safety Data Sheet (MSDS), and Allergen Statement. Our GMP-certified production ensures batch-to-batch consistency and traceability.
Sourcing Support
We offer flexible packaging and can provide samples for pre-shipment testing. Our technical team is available to assist with grade selection (Feed, Food, or Supplement Grade), application guidance, and custom formulation support — from R&D trials to full-scale commercial production.
Contact us to discuss your specific L-Lysine HCl requirements or to request samples for your formulations.
Parameters:
-
Parameter
Specification
Product Name
L-Lysine Hydrochloride
CAS Number
657-27-2
Molecular Formula
C₆H₁₅ClN₂O₂
Molecular Weight
182.65 g/mol
Assay (Purity)
≥ 98.5% (typically 98.5–101.5% )
Appearance
White to off-white crystalline powder
Available Grades
Feed Grade, Food Grade, Supplement Grade
Standards
USP, EP, FCC
Specific Rotation
[α]²⁰/D +20.4° to +21.5°
pH (100g/L solution)
5.0 – 6.0
Loss on Drying
≤ 0.40% – 0.50%
Residue on Ignition
≤ 0.1% – 0.2%
Heavy Metals
≤ 10 ppm
Lead (Pb)
≤ 5 mg/kg
Water Solubility
65 g/100 mL at 20°C; freely soluble
Melting Point
Approx. 263°C (decomposes)
Packaging Options
1kg, 5kg, 25kg (or as per request)
Documentation
Full COA, MSDS, Allergen Statement
Storage Conditions
Store in a cool, dry place at ambient temperature. Stable under recommended storage; shelf life: 2–3 years . Incompatible with strong oxidizing agents .
-
Animal Feed

L-Lysine HCl is one of the most widely used feed additives globally. It is the first limiting amino acid for pigs and the second limiting amino acid for poultry . In cereal-based diets, lysine is typically the first amino acid to become deficient, making supplementation essential for optimizing growth performance and feed efficiency .
Key Benefits:
Supports growth performance and feed conversion rates
Enables use of lower-cost feed ingredients while maintaining performance
Reduces dietary crude protein requirements without compromising growth
Improves amino acid balance in feed formulations
Supports immune function and overall animal health
Swine: As the first limiting amino acid, L-Lysine supplementation is critical for optimizing growth performance in all stages of pig production. Typical feed grade product contains ≥98.5% L-Lysine HCl .
Poultry: As the second limiting amino acid, supplementation supports optimal growth rates, feed efficiency, and egg production. L-Lysine content is critical in broiler and layer diets .
Recommended Inclusion: Levels vary by species and production stage. Our Feed Grade L-Lysine HCl is formulated for optimal dispersion in premixes and pelleted feeds .
Dietary Supplements

L-Lysine HCl is a popular ingredient in dietary supplements targeting immune support, skin health, bone health, and sports nutrition .
Key Applications:
Immune Support & Herpes Management: Inhibits HSV-1 replication by competing with arginine; commonly used to prevent outbreaks or shorten their duration
Collagen Support: Essential for collagen production, supporting skin elasticity, wound healing, and connective tissue health
Bone Health: Supports calcium absorption and bone density
Sports Nutrition: Supports protein synthesis, muscle recovery, and lean mass maintenance
Stress Management: Helps modulate stress response via cortisol regulation
Typical Dosage: 1000–3000 mg per day, divided into one or two doses. For herpes prophylaxis, 1000 mg daily is often recommended, and up to 3000 mg in acute cases . Generally well-tolerated at recommended dosages .
Food & Beverage

L-Lysine HCl is widely used in food applications as a nutritional supplement and flavoring agent (FEMA 3847) .
Key Applications:
Nutritional Fortification: Used to enhance the amino acid profile of processed foods, cereals, and protein-based products
Infant Formula: Used to ensure adequate lysine content in humanized milk powder and specialized nutrition products
Clinical Nutrition: Used in amino acid infusion solutions and specialized nutrition formulas
Flavoring Agent: Contributes to taste development in processed products
Regulatory Status: FCC grade meets Food Chemical Codex requirements and is suitable for all food, beverage, and nutritional supplement applications . L-Lysine HCl is Generally Recognized as Safe (GRAS) for use in food products .
Personal Care & Cosmetics
L-Lysine HCl is used in personal care formulations for its hair-conditioning and skin-conditioning properties .
Key Applications:
Skin Care: Supports skin health through its role in collagen production and tissue repair
Hair Care: Functions as a hair conditioning agent, contributing to hair health and strength
Wound Healing: Supports tissue repair and regeneration
Formula Compatibility: Stable in topical formulations and compatible with a wide range of cosmetic ingredients. Incompatible with strong oxidizing agents .
Key words:
High Purity L-Lysine HCl Powder | ≥98.5% Feed, Food & Supplement Grade | CAS 657-27-2
Function:
Application:
Animal Feed

L-Lysine HCl is one of the most widely used feed additives globally. It is the first limiting amino acid for pigs and the second limiting amino acid for poultry . In cereal-based diets, lysine is typically the first amino acid to become deficient, making supplementation essential for optimizing growth performance and feed efficiency .
Key Benefits:
Supports growth performance and feed conversion rates
Enables use of lower-cost feed ingredients while maintaining performance
Reduces dietary crude protein requirements without compromising growth
Improves amino acid balance in feed formulations
Supports immune function and overall animal health
Swine: As the first limiting amino acid, L-Lysine supplementation is critical for optimizing growth performance in all stages of pig production. Typical feed grade product contains ≥98.5% L-Lysine HCl .
Poultry: As the second limiting amino acid, supplementation supports optimal growth rates, feed efficiency, and egg production. L-Lysine content is critical in broiler and layer diets .
Recommended Inclusion: Levels vary by species and production stage. Our Feed Grade L-Lysine HCl is formulated for optimal dispersion in premixes and pelleted feeds .
Dietary Supplements

L-Lysine HCl is a popular ingredient in dietary supplements targeting immune support, skin health, bone health, and sports nutrition .
Key Applications:
Immune Support & Herpes Management: Inhibits HSV-1 replication by competing with arginine; commonly used to prevent outbreaks or shorten their duration
Collagen Support: Essential for collagen production, supporting skin elasticity, wound healing, and connective tissue health
Bone Health: Supports calcium absorption and bone density
Sports Nutrition: Supports protein synthesis, muscle recovery, and lean mass maintenance
Stress Management: Helps modulate stress response via cortisol regulation
Typical Dosage: 1000–3000 mg per day, divided into one or two doses. For herpes prophylaxis, 1000 mg daily is often recommended, and up to 3000 mg in acute cases . Generally well-tolerated at recommended dosages .
Food & Beverage

L-Lysine HCl is widely used in food applications as a nutritional supplement and flavoring agent (FEMA 3847) .
Key Applications:
Nutritional Fortification: Used to enhance the amino acid profile of processed foods, cereals, and protein-based products
Infant Formula: Used to ensure adequate lysine content in humanized milk powder and specialized nutrition products
Clinical Nutrition: Used in amino acid infusion solutions and specialized nutrition formulas
Flavoring Agent: Contributes to taste development in processed products
Regulatory Status: FCC grade meets Food Chemical Codex requirements and is suitable for all food, beverage, and nutritional supplement applications . L-Lysine HCl is Generally Recognized as Safe (GRAS) for use in food products .
Personal Care & Cosmetics
L-Lysine HCl is used in personal care formulations for its hair-conditioning and skin-conditioning properties .
Key Applications:
Skin Care: Supports skin health through its role in collagen production and tissue repair
Hair Care: Functions as a hair conditioning agent, contributing to hair health and strength
Wound Healing: Supports tissue repair and regeneration
Formula Compatibility: Stable in topical formulations and compatible with a wide range of cosmetic ingredients. Incompatible with strong oxidizing agents .
About Us
Henan Liyin Biotech Co.,Ltd
We are is established in 2024,located in Zhengzhou,on the banks of the Yellow River-the revered “Mother River “of China .As a specialized supplier of human nutrition and animal health products ,the company focuses on a range of products including vitamins ,amino acids ,plant extracts ,and sweeteners,which are widely used in industries ,such as food ,health supplements,cosmetics ,feed and veterinary medicine .By integrating global product resources with the needs of international clients ,Liyin Biotech provides premium products and professional services tailored to each customer .
FAQ
How to contact ?
You can contact with us by Whatsapp:+86 15824830539, the Average Response Time is 0-4h on Work time, <24h on Non-worktime.
For every inquiry, our sales will provide the one-for-one service for you.
How about the payment terms ?
Normal orders: Company account ;Sample/small orders: Paypal(The 5-10% extrafee).About the payment term, we will negotiate alone.
How to get the samples ?
At the first time ,we can provide you the normal product <30g free sample
How to confirm the Product Quality before placing orders?
1st, you can get free samples for some products, just paythe basic cost for us.
2nd,Also you can send the specification or your quest tous, we will customize the products for you.3rd,We emphasis that our whole company make a livingwith organic chemical and customers, we absolutelyimpossible to sale any fake goods, unqualified goods, it isshame! And None False certificate/lie/illegal thing in oursales net!
Which kind of payment do you accept?
- As usually we use company account ,T/T in advance ,or at least 30% T/T in advance ,the balance can be paid by the copy of B/L
- For some countrys we can accept L/C at sight & DP at sight
- For smaples we can use Paypal (The 5-10% extra fees) or other ways
About the payment term, we will negotiate alone.
How about the shipment ?
1>For bulk goods ,we can use contaioner by sea ,1&20 and 1&40 contaioner
2>For urgently and expensive goods ,we can arrange the air lines for customers choose ,or can as customer required
3>For samples or small quantity goods ,we can use Fedex or other express ways
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