High Purity L-Theanine Powder | ≥98% Feed, Food & Supplement Grade | CAS 3081-61-6
Description:
Product Overview

L-Theanine (γ-glutamylethylamide) is a unique non-protein amino acid naturally found in green tea (Camellia sinensis), where it accounts for approximately 50% of the total amino acid content and 1–2% of the dry weight of tea leaves . Unlike protein-building amino acids, L-theanine is prized for its distinctive ability to promote relaxation without drowsiness — a state often described as "calm focus" or "relaxed alertness" .
In the brain, L-theanine influences neurotransmitter activity, increasing levels of GABA, dopamine, and serotonin, while also stimulating the production of alpha brain waves associated with relaxation and mental clarity . These properties have made L-theanine a popular ingredient in supplements targeting stress management, cognitive performance, and sleep quality.
At Henan Liyin Biotech, we supply high-purity L-Theanine in the form of a white crystalline powder, with a minimum purity of ≥98%, compliant with food grade standards. Our product is available in Feed Grade, Food Grade, and Supplement Grade to serve applications across dietary supplements, functional foods, animal nutrition, and personal care.
Why Choose Our L-Theanine?
Verified Purity: Assay ≥98% (by HPLC), ensuring consistent potency for all applications
Natural Origin: Derived from tea leaves, supporting clean-label and naturally sourced product positioning
Multi-Standard Compliance: Compliant with food grade standards, providing regulatory acceptance for food and supplement applications
Proven Safety Profile: L-theanine has been recognized as GRAS (Generally Recognized as Safe) by the U.S. FDA and shows a favorable safety profile in clinical studies
Complete Traceability: Each batch is accompanied by a comprehensive Certificate of Analysis (COA)
Flexible Packaging: Available in packaging options from 1kg to bulk quantities
Key Functional Properties

Cognitive Performance & Focus
A 2025 systematic review and meta-analysis of 31 randomized controlled trials (n=1168) published in Molecular Psychiatry found that a single 200 mg dose of L-theanine taken 30–60 minutes before cognitive testing significantly improved choice reaction time, indicating enhanced attention and cognitive processing . The same study also found a significant reduction in depressive symptoms following a single dose in healthy individuals .
Relaxation & Stress Reduction
L-theanine promotes relaxation by increasing alpha brain wave activity, a state associated with calm, focused attention . Unlike sedatives, L-theanine induces relaxation without drowsiness, making it suitable for daytime use . It modulates stress responses by influencing neurotransmitter levels, including GABA, dopamine, and serotonin .
Sleep Support
Research suggests L-theanine may help improve sleep quality by promoting relaxation before bedtime, though it is not a traditional sleep aid that induces sleep directly . Clinical studies have shown that L-theanine reduces stress, improves quality of sleep, and diminishes symptoms associated with premenstrual syndrome .
Cardiovascular Health
L-theanine has been shown to support cardiovascular function through multiple mechanisms: regulating nitric oxide (NO) levels, lowering LDL (low-density lipoprotein) levels, and helping to normalize circadian rhythms . Animal studies have reported that doses of L-theanine up to 2000 mg/kg produced significant reduction in blood pressure in spontaneously hypertensive rats .

Antioxidant & Immune Support
L-theanine exhibits strong antioxidant activity, reducing oxidative damage by decreasing reactive oxygen species (ROS) synthesis and lipid peroxidation while increasing antioxidant enzyme activity (SOD, CAT, GSH) . It also supports immune function by enhancing γδ T-cell proliferation and increasing spleen weight, potentially reducing viral infection risk .
Hepatoprotective Effects
L-theanine has demonstrated hepatoprotective properties through the downregulation of inflammatory responses, initiation of nitric oxide synthesis, and glutathione production . Studies have shown that tea consumption (>2 cups per day) is linked to lower occurrence of chronic liver disease, with L-theanine potentially mediating these hepatoprotective effects .
Quality Assurance & Documentation

All batches undergo rigorous quality control, including:
Assay by HPLC: ≥98%
Heavy Metal Screening: Lead ≤ 5 mg/kg, Arsenic ≤ 2 mg/kg
Microbiological Testing: For safety and purity
pH and Solubility: Verified against specifications
Loss on Drying and Residue on Ignition: To ensure stability and purity
We provide complete documentation with every shipment, including Certificate of Analysis (COA), Material Safety Data Sheet (MSDS), and Allergen Statement. Our GMP-certified production ensures batch-to-batch consistency and traceability.
Sourcing Support
We offer flexible packaging and can provide samples for pre-shipment testing. Our technical team is available to assist with grade selection (Feed, Food, or Supplement Grade), application guidance, and custom formulation support — from R&D trials to full-scale commercial production.
Contact us to discuss your specific L-Theanine requirements or to request samples for your formulations.
Parameters:
-
Parameter
Specification
Product Name
L-Theanine
CAS Number
3081-61-6
Molecular Formula
C₇H₁₄N₂O₃
Molecular Weight
174.2 g/mol
Assay (Purity)
≥ 98% (by HPLC)
Appearance
White to off-white crystalline powder
Available Grades
Feed Grade, Food Grade, Supplement Grade
pH (1g/100mL)
5.0 – 6.0
Loss on Drying
≤ 0.5%
Residue on Ignition
≤ 0.1%
Heavy Metals
≤ 10 ppm
Lead (Pb)
≤ 5 mg/kg
Arsenic (As)
≤ 2 mg/kg
Packaging Options
1kg, 5kg, 25kg (or as per request)
Documentation
Full COA, MSDS, Allergen Statement
Storage Conditions
Store in a cool, dry place at room temperature, protected from light. Stable for up to 3 years under recommended storage .
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L‑Theanine serves as a natural anti‑stress ingredient for swine and poultry. It alleviates breeding‑induced stress, improves feed intake, optimizes growth performance and strengthens animal immunity.
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Dietary Supplements

L-Theanine is a popular ingredient in supplements targeting stress management, cognitive performance, sleep quality, and mood support. Its ability to promote relaxation without drowsiness makes it suitable for daytime use, while its sleep-supporting properties make it valuable for evening formulations.
Key Applications:
Stress & Relaxation: Supports calm, focused attention without sedation
Cognitive Performance: Improves reaction time and attention, particularly when taken 30–60 minutes before cognitive tasks
Mood Support: Has shown potential antidepressant effects in healthy individuals
Sleep Quality: Promotes relaxation before bedtime and improves overall sleep quality
Caffeine Synergy: Often combined with caffeine in "calm energy" products; L-theanine may help mitigate the jittery effects of caffeine while maintaining alertness
Typical Dosage: Effective doses range from 50 to 200 mg per serving . The meta-analysis found that 200 mg taken 30–60 minutes before cognitive testing showed significant benefits for attention .
Food & Beverage

L-Theanine is increasingly used in functional foods and beverages for its flavor-enhancing and relaxation-promoting properties. It is valued as a food additive in the Japanese and global markets.
Key Applications:
Functional Beverages: Added to teas, ready-to-drink beverages, and energy drinks to provide a calm, focused effect
Flavor Enhancer: Improves the taste of green tea and other beverages; masks bitterness and provides umami flavor
Confectionery: Added to candies and chocolates at levels around 72 mg per serving to promote relaxation
Food Fortification: Used as a nutritional supplement in functional foods
Regulatory Status: Approved as a food additive in Japan and recognized as GRAS in the U.S. .
Animal Feed

L-Theanine is emerging as a promising natural feed additive in animal nutrition, supported by a growing body of research . As a non-toxic phytogenic compound, it offers multiple benefits aligned with organic livestock production concepts .
Key Applications:
Stress Reduction: Acts as an anti-stressor by decreasing corticosterone, dopamine, and noradrenaline levels, which may help animals cope with transportation, handling, and environmental stress
Immune Support: Enhances immune function through T-cell proliferation and increased spleen weight
Growth Promotion: Supports growth performance as a natural feed additive
Hepatoprotective: May help protect liver function in livestock
Recommended Use: Research on dietary supplementation in poultry and livestock is ongoing, with L-theanine considered a potential natural feed additive with antistressor and hepatoprotective properties .
Regulatory Status: Evaluated as a safe and non-toxic phytogenic food additive for animal nutrition .
Personal Care & Cosmetics
L-Theanine is valued in personal care formulations for its antioxidant and skin-conditioning properties.
Key Applications:
Skin Protection: Exhibits antioxidant activity that may help protect skin from environmental stressors
Anti-Aging: Supports cellular health through its antioxidant and anti-inflammatory properties
Soothing Formulations: Compatible with calming and stress-relief products
Formula Compatibility: Stable in topical formulations and compatible with a wide range of cosmetic ingredients.
Key words:
High Purity L-Theanine Powder | ≥98% Feed, Food & Supplement Grade | CAS 3081-61-6
Function:
L‑Theanine serves as a natural anti‑stress ingredient for swine and poultry. It alleviates breeding‑induced stress, improves feed intake, optimizes growth performance and strengthens animal immunity.
Application:
Dietary Supplements

L-Theanine is a popular ingredient in supplements targeting stress management, cognitive performance, sleep quality, and mood support. Its ability to promote relaxation without drowsiness makes it suitable for daytime use, while its sleep-supporting properties make it valuable for evening formulations.
Key Applications:
Stress & Relaxation: Supports calm, focused attention without sedation
Cognitive Performance: Improves reaction time and attention, particularly when taken 30–60 minutes before cognitive tasks
Mood Support: Has shown potential antidepressant effects in healthy individuals
Sleep Quality: Promotes relaxation before bedtime and improves overall sleep quality
Caffeine Synergy: Often combined with caffeine in "calm energy" products; L-theanine may help mitigate the jittery effects of caffeine while maintaining alertness
Typical Dosage: Effective doses range from 50 to 200 mg per serving . The meta-analysis found that 200 mg taken 30–60 minutes before cognitive testing showed significant benefits for attention .
Food & Beverage

L-Theanine is increasingly used in functional foods and beverages for its flavor-enhancing and relaxation-promoting properties. It is valued as a food additive in the Japanese and global markets.
Key Applications:
Functional Beverages: Added to teas, ready-to-drink beverages, and energy drinks to provide a calm, focused effect
Flavor Enhancer: Improves the taste of green tea and other beverages; masks bitterness and provides umami flavor
Confectionery: Added to candies and chocolates at levels around 72 mg per serving to promote relaxation
Food Fortification: Used as a nutritional supplement in functional foods
Regulatory Status: Approved as a food additive in Japan and recognized as GRAS in the U.S. .
Animal Feed

L-Theanine is emerging as a promising natural feed additive in animal nutrition, supported by a growing body of research . As a non-toxic phytogenic compound, it offers multiple benefits aligned with organic livestock production concepts .
Key Applications:
Stress Reduction: Acts as an anti-stressor by decreasing corticosterone, dopamine, and noradrenaline levels, which may help animals cope with transportation, handling, and environmental stress
Immune Support: Enhances immune function through T-cell proliferation and increased spleen weight
Growth Promotion: Supports growth performance as a natural feed additive
Hepatoprotective: May help protect liver function in livestock
Recommended Use: Research on dietary supplementation in poultry and livestock is ongoing, with L-theanine considered a potential natural feed additive with antistressor and hepatoprotective properties .
Regulatory Status: Evaluated as a safe and non-toxic phytogenic food additive for animal nutrition .
Personal Care & Cosmetics
L-Theanine is valued in personal care formulations for its antioxidant and skin-conditioning properties.
Key Applications:
Skin Protection: Exhibits antioxidant activity that may help protect skin from environmental stressors
Anti-Aging: Supports cellular health through its antioxidant and anti-inflammatory properties
Soothing Formulations: Compatible with calming and stress-relief products
Formula Compatibility: Stable in topical formulations and compatible with a wide range of cosmetic ingredients.
About Us
Henan Liyin Biotech Co.,Ltd
We are is established in 2024,located in Zhengzhou,on the banks of the Yellow River-the revered “Mother River “of China .As a specialized supplier of human nutrition and animal health products ,the company focuses on a range of products including vitamins ,amino acids ,plant extracts ,and sweeteners,which are widely used in industries ,such as food ,health supplements,cosmetics ,feed and veterinary medicine .By integrating global product resources with the needs of international clients ,Liyin Biotech provides premium products and professional services tailored to each customer .
FAQ
How to contact ?
You can contact with us by Whatsapp:+86 15824830539, the Average Response Time is 0-4h on Work time, <24h on Non-worktime.
For every inquiry, our sales will provide the one-for-one service for you.
How about the payment terms ?
Normal orders: Company account ;Sample/small orders: Paypal(The 5-10% extrafee).About the payment term, we will negotiate alone.
How to get the samples ?
At the first time ,we can provide you the normal product <30g free sample
How to confirm the Product Quality before placing orders?
1st, you can get free samples for some products, just paythe basic cost for us.
2nd,Also you can send the specification or your quest tous, we will customize the products for you.3rd,We emphasis that our whole company make a livingwith organic chemical and customers, we absolutelyimpossible to sale any fake goods, unqualified goods, it isshame! And None False certificate/lie/illegal thing in oursales net!
Which kind of payment do you accept?
- As usually we use company account ,T/T in advance ,or at least 30% T/T in advance ,the balance can be paid by the copy of B/L
- For some countrys we can accept L/C at sight & DP at sight
- For smaples we can use Paypal (The 5-10% extra fees) or other ways
About the payment term, we will negotiate alone.
How about the shipment ?
1>For bulk goods ,we can use contaioner by sea ,1&20 and 1&40 contaioner
2>For urgently and expensive goods ,we can arrange the air lines for customers choose ,or can as customer required
3>For samples or small quantity goods ,we can use Fedex or other express ways
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