High Purity L-Methionine Powder | ≥98% Feed, Food & Supplement Grade | CAS 63-68-3
Description:
Product Overview

L-Methionine is an essential sulfur-containing amino acid that plays a critical role in protein synthesis, methylation reactions, and sulfur metabolism. As one of the nine essential amino acids, it cannot be synthesized by the body and must be obtained through diet or supplementation . L-Methionine serves as the precursor for S-adenosyl-L-methionine (SAMe), a key methyl donor involved in numerous biological processes including liver function, immune response, and neurotransmitter synthesis .
At Henan Liyin Biotech, we supply high-purity L-Methionine in the form of a white crystalline powder, with a minimum purity of ≥98% , compliant with USP, EP, and FCC standards. Our product is available in Feed Grade, Food Grade, and Supplement Grade to serve applications across animal nutrition, human food, dietary supplements, and personal care.
Why Choose Our L-Methionine?

Verified Purity: Assay ≥98.0% (by HPLC), with typical batch results exceeding 99%, ensuring consistent potency for all applications.
Multi-Standard Compliance: Meets USP, EP, and FCC specifications, providing global regulatory acceptance.
Superior Bioavailability: The natural L-form is the biologically functional form directly utilized by intestinal cells, particularly important for young animals .
Complete Traceability: Each batch is accompanied by a comprehensive Certificate of Analysis (COA), including testing for purity, heavy metals, and microbiological contaminants.
Flexible Packaging: Available in packaging options from 1kg to bulk quantities to suit your production needs.
Key Functional Properties

Protein Synthesis & Growth
L-Methionine is the first limiting amino acid in poultry and livestock diets . It is essential for protein synthesis and serves as a critical building block for growth and development in both animals and humans .
Transmethylation & Sulfur Metabolism
L-Methionine is the primary precursor for S-adenosyl-L-methionine (SAMe), which functions as a major methyl donor in the body. This methylation process is crucial for DNA synthesis, neurotransmitter production, and liver function . It also participates in transsulfuration pathways for the synthesis of sulfur-containing bioactive compounds such as glutathione and taurine .
Antioxidant Support
As a precursor to glutathione, one of the body's most important antioxidants, L-Methionine helps protect cells from oxidative stress and supports liver health . Its metabolic product glutathione plays a key role in regulating immune response and has antiviral action .
Gut Health & Immunity
Recent research has demonstrated that L-Methionine supplementation modulates gut microbiota and improves the expression of tight junction genes in intestinal cells, directly supporting immune function and intestinal integrity .
Quality Assurance & Documentation

All batches undergo rigorous quality control, including:
Assay by HPLC: ≥98.0%
Heavy Metal Screening: Lead, arsenic, and other contaminants
Microbiological Testing: For safety and purity
Specific Rotation and pH: Verified against USP/EP/FCC specifications
Loss on Drying and Residue on Ignition: To ensure stability
We provide complete documentation with every shipment, including Certificate of Analysis (COA), Material Safety Data Sheet (MSDS), and Allergen Statement. Our GMP-certified production ensures batch-to-batch consistency and traceability.
Sourcing Support
We offer flexible packaging and can provide samples for pre-shipment testing. Our technical team is available to assist with grade selection (Feed, Food, or Supplement Grade), application guidance, and custom formulation support — from R&D trials to full-scale commercial production.
Contact us to discuss your specific L-Methionine requirements or to request samples for your formulations.
Parameters:
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Parameter
Specification
Product Name
L-Methionine
CAS Number
63-68-3
Molecular Formula
C₅H₁₁NO₂S
Molecular Weight
149.21 g/mol
Assay (Purity)
≥ 98.0% (by HPLC)
Appearance
White crystalline powder
Available Grades
Feed Grade, Food Grade, Supplement Grade
Standards
USP, EP, FCC
Specific Rotation
[α]²⁰/D +23.0° to +25.0°
pH (0.5M solution)
5.0 – 7.0
Loss on Drying
≤ 0.5%
Residue on Ignition
≤ 0.1%
Heavy Metals
≤ 10 ppm
Chloride (Cl)
≤ 0.02%
Sulfate (SO₄)
≤ 0.02%
Packaging Options
1kg, 5kg, 25kg (or as per request)
Documentation
Full COA, MSDS, Allergen Statement
Storage Conditions
Storage Conditions Store in a cool, dry place, protected from light. Incompatible with strong oxidizing agents .
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L-Methionine is an essential sulfur-containing amino acid that plays a critical role in protein synthesis and serves as the primary precursor to SAMe (S-adenosyl-L-methionine), a key methyl donor involved in liver function, neurotransmitter production, and DNA methylation. In animal nutrition, it is the first limiting amino acid in poultry and livestock diets, essential for growth performance, feed efficiency, and immune function. Available in Feed, Food, and Supplement Grades with ≥98% purity.
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Animal Feed

L-Methionine is the first limiting amino acid in corn-soybean meal-based diets for poultry and a critical nutrient in swine and aquaculture nutrition . It is indispensable for energy metabolism, physiology, performance, and feed utilization capacity .
Poultry
Recent research has demonstrated that L-Methionine supplementation improves average daily gain (ADG), feed conversion ratio (FCR), carcass percentage, and antioxidant status in broilers . Studies indicate that L-Methionine may have superior bioavailability compared to DL-Methionine in young growing broilers, particularly during the starter phase . The natural L-form is directly utilized by intestinal cells, whereas D-Methionine must first be converted to L-Methionine via enzymatic reactions .
Swine
Supplementation with L-Methionine in finishing pig diets supports growth performance and feed efficiency. Studies have shown that L-Methionine effectively meets the standardized ileal digestible methionine requirements in swine rations .
Aquaculture
Methionine is one of the most limiting essential amino acids in aquafeeds . L-Methionine is used in fish and shrimp feeds to support growth performance and antioxidant potential, particularly under challenging conditions such as high water temperatures .
Gut Health
Feed grade L-Methionine has been shown to increase the expression of tight junction genes in intestinal cells, directly supporting immunity and maintaining intestinal integrity. It also modulates gut microbiota, increasing commensal bacteria while decreasing pathogenic populations .
Recommended Inclusion: Levels vary by species and production stage. Typical feed grade product contains ≥98% L-Methionine, with the natural L-form offering a bioavailability advantage over DL-Methionine in young animals .
Food & Beverage

In human nutrition, L-Methionine is an essential amino acid used for food fortification and nutritional supplementation . Most people in the U.S. get adequate methionine from protein-rich diets (meat, fish, eggs, dairy), but it is also available in supplements .
Food Fortification: Used to improve the amino acid profile of plant-based proteins, particularly in soy-based products where methionine is a limiting amino acid . It helps enhance the nutritional value of foods and beverages.
Flavoring Agent: Methionine is used in oral pharmaceutical formulations as a flavoring agent .
Regulatory Status: FCC grade is suitable for food, beverage, and nutritional supplement applications. Methionine is included in the FDA Inactive Ingredients Database .
Dietary Supplements

L-Methionine is a popular ingredient in dietary supplements targeting liver health, methylation support, and overall wellness.
SAMe Precursor: The body converts L-Methionine into SAMe (S-Adenosyl-L-methionine), which has been studied for its potential role in supporting mood, joint health, and liver function .
Lipotropic Support: L-Methionine functions as a lipotropic agent, supporting fat metabolism and liver health .
Antioxidant Support: Through its role in glutathione production, L-Methionine helps protect cells from oxidative damage .
Typical Dosage: Supplementation levels vary by intended use. Generally recognized as safe when taken as directed .
Personal Care & Cosmetics
L-Methionine is used in personal care formulations for its skin-conditioning and hair-conditioning properties. It helps normalize oil gland sebum production and is used as a texturizer in cosmetic creams .
Skin Care: Supports healthy skin function and may help with sulfur metabolism in skin tissues.
Hair Care: Its sulfur content contributes to hair health and strength. Methionine is sometimes used in formulations targeting hair growth and condition .
Formula Compatibility: Stable in topical formulations and compatible with a wide range of cosmetic ingredients. Methionine is sensitive to light and should be stored in a cool, dark place .
Key words:
High Purity L-Methionine Powder | ≥98% Feed, Food & Supplement Grade | CAS 63-68-3
Function:
L-Methionine is an essential sulfur-containing amino acid that plays a critical role in protein synthesis and serves as the primary precursor to SAMe (S-adenosyl-L-methionine), a key methyl donor involved in liver function, neurotransmitter production, and DNA methylation. In animal nutrition, it is the first limiting amino acid in poultry and livestock diets, essential for growth performance, feed efficiency, and immune function. Available in Feed, Food, and Supplement Grades with ≥98% purity.
Application:
Animal Feed

L-Methionine is the first limiting amino acid in corn-soybean meal-based diets for poultry and a critical nutrient in swine and aquaculture nutrition . It is indispensable for energy metabolism, physiology, performance, and feed utilization capacity .
Poultry
Recent research has demonstrated that L-Methionine supplementation improves average daily gain (ADG), feed conversion ratio (FCR), carcass percentage, and antioxidant status in broilers . Studies indicate that L-Methionine may have superior bioavailability compared to DL-Methionine in young growing broilers, particularly during the starter phase . The natural L-form is directly utilized by intestinal cells, whereas D-Methionine must first be converted to L-Methionine via enzymatic reactions .
Swine
Supplementation with L-Methionine in finishing pig diets supports growth performance and feed efficiency. Studies have shown that L-Methionine effectively meets the standardized ileal digestible methionine requirements in swine rations .
Aquaculture
Methionine is one of the most limiting essential amino acids in aquafeeds . L-Methionine is used in fish and shrimp feeds to support growth performance and antioxidant potential, particularly under challenging conditions such as high water temperatures .
Gut Health
Feed grade L-Methionine has been shown to increase the expression of tight junction genes in intestinal cells, directly supporting immunity and maintaining intestinal integrity. It also modulates gut microbiota, increasing commensal bacteria while decreasing pathogenic populations .
Recommended Inclusion: Levels vary by species and production stage. Typical feed grade product contains ≥98% L-Methionine, with the natural L-form offering a bioavailability advantage over DL-Methionine in young animals .
Food & Beverage

In human nutrition, L-Methionine is an essential amino acid used for food fortification and nutritional supplementation . Most people in the U.S. get adequate methionine from protein-rich diets (meat, fish, eggs, dairy), but it is also available in supplements .
Food Fortification: Used to improve the amino acid profile of plant-based proteins, particularly in soy-based products where methionine is a limiting amino acid . It helps enhance the nutritional value of foods and beverages.
Flavoring Agent: Methionine is used in oral pharmaceutical formulations as a flavoring agent .
Regulatory Status: FCC grade is suitable for food, beverage, and nutritional supplement applications. Methionine is included in the FDA Inactive Ingredients Database .
Dietary Supplements

L-Methionine is a popular ingredient in dietary supplements targeting liver health, methylation support, and overall wellness.
SAMe Precursor: The body converts L-Methionine into SAMe (S-Adenosyl-L-methionine), which has been studied for its potential role in supporting mood, joint health, and liver function .
Lipotropic Support: L-Methionine functions as a lipotropic agent, supporting fat metabolism and liver health .
Antioxidant Support: Through its role in glutathione production, L-Methionine helps protect cells from oxidative damage .
Typical Dosage: Supplementation levels vary by intended use. Generally recognized as safe when taken as directed .
Personal Care & Cosmetics
L-Methionine is used in personal care formulations for its skin-conditioning and hair-conditioning properties. It helps normalize oil gland sebum production and is used as a texturizer in cosmetic creams .
Skin Care: Supports healthy skin function and may help with sulfur metabolism in skin tissues.
Hair Care: Its sulfur content contributes to hair health and strength. Methionine is sometimes used in formulations targeting hair growth and condition .
Formula Compatibility: Stable in topical formulations and compatible with a wide range of cosmetic ingredients. Methionine is sensitive to light and should be stored in a cool, dark place .
About Us
Henan Liyin Biotech Co.,Ltd
We are is established in 2024,located in Zhengzhou,on the banks of the Yellow River-the revered “Mother River “of China .As a specialized supplier of human nutrition and animal health products ,the company focuses on a range of products including vitamins ,amino acids ,plant extracts ,and sweeteners,which are widely used in industries ,such as food ,health supplements,cosmetics ,feed and veterinary medicine .By integrating global product resources with the needs of international clients ,Liyin Biotech provides premium products and professional services tailored to each customer .
FAQ
How to contact ?
You can contact with us by Whatsapp:+86 15824830539, the Average Response Time is 0-4h on Work time, <24h on Non-worktime.
For every inquiry, our sales will provide the one-for-one service for you.
How about the payment terms ?
Normal orders: Company account ;Sample/small orders: Paypal(The 5-10% extrafee).About the payment term, we will negotiate alone.
How to get the samples ?
At the first time ,we can provide you the normal product <30g free sample
How to confirm the Product Quality before placing orders?
1st, you can get free samples for some products, just paythe basic cost for us.
2nd,Also you can send the specification or your quest tous, we will customize the products for you.3rd,We emphasis that our whole company make a livingwith organic chemical and customers, we absolutelyimpossible to sale any fake goods, unqualified goods, it isshame! And None False certificate/lie/illegal thing in oursales net!
Which kind of payment do you accept?
- As usually we use company account ,T/T in advance ,or at least 30% T/T in advance ,the balance can be paid by the copy of B/L
- For some countrys we can accept L/C at sight & DP at sight
- For smaples we can use Paypal (The 5-10% extra fees) or other ways
About the payment term, we will negotiate alone.
How about the shipment ?
1>For bulk goods ,we can use contaioner by sea ,1&20 and 1&40 contaioner
2>For urgently and expensive goods ,we can arrange the air lines for customers choose ,or can as customer required
3>For samples or small quantity goods ,we can use Fedex or other express ways
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