The company focuses on vitamins, amino acids, plant extracts, sweeteners and other series of products, which have been widely used in food, health food, cosmetics, feed, veterinary medicine and other industries.

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High Purity L-Methionine Powder | ≥98% Feed, Food & Supplement Grade | CAS 63-68-3
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  • High Purity L-Methionine Powder | ≥98% Feed, Food & Supplement Grade | CAS 63-68-3

High Purity L-Methionine Powder | ≥98% Feed, Food & Supplement Grade | CAS 63-68-3

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Description:


Product Overview

L-Methionine is an essential sulfur-containing amino acid that plays a critical role in protein synthesis, methylation reactions, and sulfur metabolism. As one of the nine essential amino acids, it cannot be synthesized by the body and must be obtained through diet or supplementation . L-Methionine serves as the precursor for S-adenosyl-L-methionine (SAMe), a key methyl donor involved in numerous biological processes including liver function, immune response, and neurotransmitter synthesis .

At Henan Liyin Biotech, we supply high-purity L-Methionine in the form of a white crystalline powder, with a minimum purity of ≥98% , compliant with USP, EP, and FCC standards. Our product is available in Feed Grade, Food Grade, and Supplement Grade to serve applications across animal nutrition, human food, dietary supplements, and personal care.

Why Choose Our L-Methionine?

Infographic highlighting key features of L-Methionine powder: essential sulfur-containing amino acid, high purity, and multiple grade availability.

Verified Purity: Assay ≥98.0% (by HPLC), with typical batch results exceeding 99%, ensuring consistent potency for all applications.

Multi-Standard Compliance: Meets USP, EP, and FCC specifications, providing global regulatory acceptance.

Superior Bioavailability: The natural L-form is the biologically functional form directly utilized by intestinal cells, particularly important for young animals .

Complete Traceability: Each batch is accompanied by a comprehensive Certificate of Analysis (COA), including testing for purity, heavy metals, and microbiological contaminants.

Flexible Packaging: Available in packaging options from 1kg to bulk quantities to suit your production needs.

Key Functional Properties

Infographic illustrating the metabolic pathways of L-Methionine including protein synthesis and SAMe-mediated methylation for liver and neurotransmitter support.

Protein Synthesis & Growth

L-Methionine is the first limiting amino acid in poultry and livestock diets . It is essential for protein synthesis and serves as a critical building block for growth and development in both animals and humans .

Transmethylation & Sulfur Metabolism

L-Methionine is the primary precursor for S-adenosyl-L-methionine (SAMe), which functions as a major methyl donor in the body. This methylation process is crucial for DNA synthesis, neurotransmitter production, and liver function . It also participates in transsulfuration pathways for the synthesis of sulfur-containing bioactive compounds such as glutathione and taurine .

Antioxidant Support

As a precursor to glutathione, one of the body's most important antioxidants, L-Methionine helps protect cells from oxidative stress and supports liver health . Its metabolic product glutathione plays a key role in regulating immune response and has antiviral action .

Gut Health & Immunity

Recent research has demonstrated that L-Methionine supplementation modulates gut microbiota and improves the expression of tight junction genes in intestinal cells, directly supporting immune function and intestinal integrity .

Quality Assurance & Documentation

Certificate of Analysis (COA) and flexible packaging options for high purity L-Methionine powder.

All batches undergo rigorous quality control, including:

Assay by HPLC: ≥98.0%

Heavy Metal Screening: Lead, arsenic, and other contaminants

Microbiological Testing: For safety and purity

Specific Rotation and pH: Verified against USP/EP/FCC specifications

Loss on Drying and Residue on Ignition: To ensure stability

We provide complete documentation with every shipment, including Certificate of Analysis (COA), Material Safety Data Sheet (MSDS), and Allergen Statement. Our GMP-certified production ensures batch-to-batch consistency and traceability.

Sourcing Support

We offer flexible packaging and can provide samples for pre-shipment testing. Our technical team is available to assist with grade selection (Feed, Food, or Supplement Grade), application guidance, and custom formulation support — from R&D trials to full-scale commercial production.

Contact us to discuss your specific L-Methionine requirements or to request samples for your formulations.

Parameters:


  • Parameter 

    Specification

    Product Name

    L-Methionine

    CAS Number

     63-68-3 

    Molecular Formula 

    C₅H₁₁NO₂S 

    Molecular Weight

     149.21 g/mol 

    Assay (Purity)

    ≥ 98.0% (by HPLC)

    Appearance

    White crystalline powder 

    Available Grades

    Feed Grade, Food Grade, Supplement Grade

    Standards

    USP, EP, FCC

    Specific Rotation

    [α]²⁰/D +23.0° to +25.0° 

    pH (0.5M solution)

    5.0 – 7.0

    Loss on Drying

     ≤ 0.5%

    Residue on Ignition

    ≤ 0.1%

    Heavy Metals

    ≤ 10 ppm

    Chloride (Cl)

    ≤ 0.02%

    Sulfate (SO₄)

    ≤ 0.02%

    Packaging Options

    1kg, 5kg, 25kg (or as per request)

    Documentation

    Full COA, MSDS, Allergen Statement

    Storage Conditions

    Storage Conditions Store in a cool, dry place, protected from light. Incompatible with strong oxidizing agents .

     

  • L-Methionine is an essential sulfur-containing amino acid that plays a critical role in protein synthesis and serves as the primary precursor to SAMe (S-adenosyl-L-methionine), a key methyl donor involved in liver function, neurotransmitter production, and DNA methylation. In animal nutrition, it is the first limiting amino acid in poultry and livestock diets, essential for growth performance, feed efficiency, and immune function. Available in Feed, Food, and Supplement Grades with ≥98% purity.

  • Animal Feed

    L-Methionine used as a feed additive in poultry and swine nutrition as the first limiting amino acid for growth and feed efficiency.

    L-Methionine is the first limiting amino acid in corn-soybean meal-based diets for poultry and a critical nutrient in swine and aquaculture nutrition . It is indispensable for energy metabolism, physiology, performance, and feed utilization capacity .

    Poultry

    Recent research has demonstrated that L-Methionine supplementation improves average daily gain (ADG), feed conversion ratio (FCR), carcass percentage, and antioxidant status in broilers . Studies indicate that L-Methionine may have superior bioavailability compared to DL-Methionine in young growing broilers, particularly during the starter phase . The natural L-form is directly utilized by intestinal cells, whereas D-Methionine must first be converted to L-Methionine via enzymatic reactions .

    Swine

    Supplementation with L-Methionine in finishing pig diets supports growth performance and feed efficiency. Studies have shown that L-Methionine effectively meets the standardized ileal digestible methionine requirements in swine rations .

    Aquaculture

    Methionine is one of the most limiting essential amino acids in aquafeeds . L-Methionine is used in fish and shrimp feeds to support growth performance and antioxidant potential, particularly under challenging conditions such as high water temperatures .

    Gut Health

    Feed grade L-Methionine has been shown to increase the expression of tight junction genes in intestinal cells, directly supporting immunity and maintaining intestinal integrity. It also modulates gut microbiota, increasing commensal bacteria while decreasing pathogenic populations .

    Recommended Inclusion: Levels vary by species and production stage. Typical feed grade product contains ≥98% L-Methionine, with the natural L-form offering a bioavailability advantage over DL-Methionine in young animals .

     Food & Beverage

    L-Methionine used for food fortification in plant-based proteins and nutritional products to improve amino acid profiles.

    In human nutrition, L-Methionine is an essential amino acid used for food fortification and nutritional supplementation . Most people in the U.S. get adequate methionine from protein-rich diets (meat, fish, eggs, dairy), but it is also available in supplements .

    Food Fortification: Used to improve the amino acid profile of plant-based proteins, particularly in soy-based products where methionine is a limiting amino acid . It helps enhance the nutritional value of foods and beverages.

    Flavoring Agent: Methionine is used in oral pharmaceutical formulations as a flavoring agent .

    Regulatory Status: FCC grade is suitable for food, beverage, and nutritional supplement applications. Methionine is included in the FDA Inactive Ingredients Database .

    Dietary Supplements

    L-Methionine used in dietary supplements for liver health, methylation support, and antioxidant defense.

    L-Methionine is a popular ingredient in dietary supplements targeting liver health, methylation support, and overall wellness.

    SAMe Precursor: The body converts L-Methionine into SAMe (S-Adenosyl-L-methionine), which has been studied for its potential role in supporting mood, joint health, and liver function .

    Lipotropic Support: L-Methionine functions as a lipotropic agent, supporting fat metabolism and liver health .

    Antioxidant Support: Through its role in glutathione production, L-Methionine helps protect cells from oxidative damage .

    Typical Dosage: Supplementation levels vary by intended use. Generally recognized as safe when taken as directed .

    Personal Care & Cosmetics

    L-Methionine is used in personal care formulations for its skin-conditioning and hair-conditioning properties. It helps normalize oil gland sebum production and is used as a texturizer in cosmetic creams .

    Skin Care: Supports healthy skin function and may help with sulfur metabolism in skin tissues.

    Hair Care: Its sulfur content contributes to hair health and strength. Methionine is sometimes used in formulations targeting hair growth and condition .

    Formula Compatibility: Stable in topical formulations and compatible with a wide range of cosmetic ingredients. Methionine is sensitive to light and should be stored in a cool, dark place .


Key words:

High Purity L-Methionine Powder | ≥98% Feed, Food & Supplement Grade | CAS 63-68-3

Function:

L-Methionine is an essential sulfur-containing amino acid that plays a critical role in protein synthesis and serves as the primary precursor to SAMe (S-adenosyl-L-methionine), a key methyl donor involved in liver function, neurotransmitter production, and DNA methylation. In animal nutrition, it is the first limiting amino acid in poultry and livestock diets, essential for growth performance, feed efficiency, and immune function. Available in Feed, Food, and Supplement Grades with ≥98% purity.

Application:

Animal Feed

L-Methionine used as a feed additive in poultry and swine nutrition as the first limiting amino acid for growth and feed efficiency.

L-Methionine is the first limiting amino acid in corn-soybean meal-based diets for poultry and a critical nutrient in swine and aquaculture nutrition . It is indispensable for energy metabolism, physiology, performance, and feed utilization capacity .

Poultry

Recent research has demonstrated that L-Methionine supplementation improves average daily gain (ADG), feed conversion ratio (FCR), carcass percentage, and antioxidant status in broilers . Studies indicate that L-Methionine may have superior bioavailability compared to DL-Methionine in young growing broilers, particularly during the starter phase . The natural L-form is directly utilized by intestinal cells, whereas D-Methionine must first be converted to L-Methionine via enzymatic reactions .

Swine

Supplementation with L-Methionine in finishing pig diets supports growth performance and feed efficiency. Studies have shown that L-Methionine effectively meets the standardized ileal digestible methionine requirements in swine rations .

Aquaculture

Methionine is one of the most limiting essential amino acids in aquafeeds . L-Methionine is used in fish and shrimp feeds to support growth performance and antioxidant potential, particularly under challenging conditions such as high water temperatures .

Gut Health

Feed grade L-Methionine has been shown to increase the expression of tight junction genes in intestinal cells, directly supporting immunity and maintaining intestinal integrity. It also modulates gut microbiota, increasing commensal bacteria while decreasing pathogenic populations .

Recommended Inclusion: Levels vary by species and production stage. Typical feed grade product contains ≥98% L-Methionine, with the natural L-form offering a bioavailability advantage over DL-Methionine in young animals .

 Food & Beverage

L-Methionine used for food fortification in plant-based proteins and nutritional products to improve amino acid profiles.

In human nutrition, L-Methionine is an essential amino acid used for food fortification and nutritional supplementation . Most people in the U.S. get adequate methionine from protein-rich diets (meat, fish, eggs, dairy), but it is also available in supplements .

Food Fortification: Used to improve the amino acid profile of plant-based proteins, particularly in soy-based products where methionine is a limiting amino acid . It helps enhance the nutritional value of foods and beverages.

Flavoring Agent: Methionine is used in oral pharmaceutical formulations as a flavoring agent .

Regulatory Status: FCC grade is suitable for food, beverage, and nutritional supplement applications. Methionine is included in the FDA Inactive Ingredients Database .

Dietary Supplements

L-Methionine used in dietary supplements for liver health, methylation support, and antioxidant defense.

L-Methionine is a popular ingredient in dietary supplements targeting liver health, methylation support, and overall wellness.

SAMe Precursor: The body converts L-Methionine into SAMe (S-Adenosyl-L-methionine), which has been studied for its potential role in supporting mood, joint health, and liver function .

Lipotropic Support: L-Methionine functions as a lipotropic agent, supporting fat metabolism and liver health .

Antioxidant Support: Through its role in glutathione production, L-Methionine helps protect cells from oxidative damage .

Typical Dosage: Supplementation levels vary by intended use. Generally recognized as safe when taken as directed .

Personal Care & Cosmetics

L-Methionine is used in personal care formulations for its skin-conditioning and hair-conditioning properties. It helps normalize oil gland sebum production and is used as a texturizer in cosmetic creams .

Skin Care: Supports healthy skin function and may help with sulfur metabolism in skin tissues.

Hair Care: Its sulfur content contributes to hair health and strength. Methionine is sometimes used in formulations targeting hair growth and condition .

Formula Compatibility: Stable in topical formulations and compatible with a wide range of cosmetic ingredients. Methionine is sensitive to light and should be stored in a cool, dark place .

About Us

Henan Liyin Biotech Co.,Ltd

We are is established in 2024,located in Zhengzhou,on the banks of the Yellow River-the revered “Mother River “of China .As a specialized supplier of human nutrition and animal health products ,the company focuses on a range of products including vitamins ,amino acids ,plant extracts ,and sweeteners,which are widely used in industries ,such as food ,health supplements,cosmetics ,feed and veterinary medicine .By integrating global product resources with the needs of international clients ,Liyin Biotech provides premium products and professional services tailored to each customer .

Henan Liyin Biotech Co.,Ltd

FAQ

How to contact ?


You can contact with us by Whatsapp:+86 15824830539, the Average Response Time is 0-4h on Work time, <24h on Non-worktime.
For every inquiry, our sales will provide the one-for-one service for you.

How about the payment terms ?


Normal orders: Company account ;Sample/small orders: Paypal(The 5-10% extrafee).About the payment term, we will negotiate alone.

How to get the samples ?


At the first time ,we can provide you the normal product <30g free sample

How to confirm the Product Quality before placing orders?


1st, you can get free samples for some products, just paythe basic cost for us.
2nd,Also you can send the specification or your quest tous, we will customize the products for you.3rd,We emphasis that our whole company make a livingwith organic chemical and customers, we absolutelyimpossible to sale any fake goods, unqualified goods, it isshame! And None False certificate/lie/illegal thing in oursales net!

Which kind of payment do you accept?


  1. As usually  we  use company account ,T/T in advance ,or at least 30% T/T in advance ,the balance can be paid by the copy of B/L 
  2. For some countrys we can accept  L/C at sight & DP at sight  
  3. For smaples we can use Paypal (The 5-10% extra fees) or other ways  

About the payment term, we will negotiate alone.

How about the shipment ?


1>For bulk goods ,we can use contaioner by sea ,1&20 and 1&40 contaioner 

2>For urgently and expensive goods ,we can arrange the air lines for customers choose ,or can as customer required 

3>For samples or small quantity goods ,we can use Fedex or other express ways 

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